CEREBRAL VENOUS SINUS THROMBOSIS WITH GOOD RESPONSE TO HEPARINIZATION THERAPY: TWO CASE REPORT AND DIAGNOSTIC ALGORITHM

Authors

  • Carolin Tiara Lestari Indah Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia
  • Kumara Tini Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia
  • Ni Made Susilawathi Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia
  • Ida Ayu Sri Wijayanti Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia
  • Ni Putu Ayu Putri Mahadewi Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali
  • Anak Ayu Agung Pramaswari Neurology Department Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia
  • I Gusti Ngurah Mahaalit Aribawa Anesthesiology and Intensive Therapy Department Faculty of Medicine Universitas Udayana/ Universitas Udayana Hospital, Denpasar, Bali, Indonesia
  • Putu Utami Dewi Radiology Department Faculty of Medicine Universitas Udayana/ Universitas Udayana Hospital, Denpasar, Bali, Indonesia
  • Cokorda Istri Yuliandari Krisnawardhani Kumbara Internal Medicine Department Faculty of Medicine Universitas Udayana/ Universitas Udayana Hospital, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.21776/ub.mnj.2024.010.02.17

Keywords:

Cerebral venous sinus thrombosis, heparinization, venous occlusion, algorithm

Abstract

Cerebral venous sinus thrombosis (CVST) is an uncommon condition of cerebral venous sinus thrombosis with a varied clinical presentation that can be diagnostically challenging. Intravenous heparin is the optimal immediate anticoagulant according to the European Academy of Neurology (EAN) guideline 2017. This report aims to describe highly suspicious CVST clinical features and suggest a diagnostic algorithm based on two cases of CVST found in our center. The first case is a 52-year-old man who presented with serial seizures preceded by subacute headache and diparesis. Non-contrast head CT (NCCT) showed multifocal haemorrhages and cord signs. The second case is a 19-year-old woman who presented with slowly decreased consciousness, headache, and a history of upper respiratory infection. Diffuse cerebral edema was revealed in NCCT. Both of these patients had thrombosis in superior sagittal sinus, right transverse, and sigmoid sinus. Heparinization was conducted and continued with rivaroxaban with a good response. CVST is rare case and often unrecognized; since it has serious complications, early diagnosis and treatment improve prognosis and survival.

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Published

2024-05-19

How to Cite

Indah, C. T. L., Tini, K., Susilawathi, N. M., Wijayanti, I. A. S., Mahadewi, N. P. A. P., Pramaswari, A. A. A., Mahaalit Aribawa, I. G. N., Dewi, P. U., & Krisnawardhani Kumbara, C. I. Y. (2024). CEREBRAL VENOUS SINUS THROMBOSIS WITH GOOD RESPONSE TO HEPARINIZATION THERAPY: TWO CASE REPORT AND DIAGNOSTIC ALGORITHM. MNJ (Malang Neurology Journal), 10(2), 176–179. https://doi.org/10.21776/ub.mnj.2024.010.02.17

Issue

Vol. 10 No. 2 (2024): July 2024

Section

Case Report

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Copyright (c) 2024 MNJ (Malang Neurology Journal)

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Creative Commons License
This work is licensed under a
Creative Commons Attribution-NonCommercial 4.0 International License