MEASUREMENT OF MIDSAGITTAL CORPUS CALLOSUM AREA WITH THE MODIFIED CAVALIERI METHOD IN HEALTHY RIGHT- AND LEFT-HANDED TURKISH ADULTS

Mete Ozdikici
  MNJ, pp. 23-26  

Abstract


Background: Numerous studies have been published on the anatomy and physiology of the corpus callosum (CC). There are many contradictory studies in the literature about the changes in the size of the CC by handedness, sex, and age.

Objective: This study was carried out to examine the morphometric influence of these factors (handedness, sex, and age) on the CC in healthy Turkish adults

Methods: Two hundred thirty-seven normal individuals, 101 males, and 136 females, divided into 5 age groups (20-29, 30-39, 40-49, 50-59, and 60-69) were subjected to magnetic resonance imaging (MRI) study of the brain. Of the 237 subjects, 27 males and 36 females were left-handed. Midsagittal corpus callosum area (CCA) was represented by the mean ± standard deviation of the age groups in square centimeters, and also comparisons of the right- and left-handed were also represented in Table 1. For statistical evaluation, the SPSS 15.0 was used. All statistical tests were set at a 95% confidence level (p<0.05).

Results: The range of the reference values (mean values and standard deviation) for the performed measurements in the age groups and for men, women, and total are presented; and comparisons of the right- and left-handed were also represented in Table 1. In our study, CCA was found 6,46±1,05 cm2 in all men and 6,17±0,82 cm2 in all women. The values of CCA are 6,50±1,05 cm2 in right-handed men and 6,34±1,03 cm2 in left-handed men, 6,16±0,80 cm2 in right-handed women, and 6,19±0,91 cm2 in left-handed women. There is a statistically significant difference between males and females in CCA (p<0.05). There is no statistically significant difference between the age groups for CCA, and there is no difference between right- and left-handed for men and women (p>0.05) (Table 2).

Conclusion: The results showed no statistical significance of the effect of age or handedness on the surface area of the CC. However, it was statistically significant that the size of men's CC was higher than that of women.

Keywords:  Midsagittal corpus callosum area, modified Cavalieri method, handedness, Turkish adults, magnetic resonance imaging.

Keywords


Midsagittal corpus callosum area; modified Cavalieri method; handedness; Turkish adults; magnetic resonance imaging

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References


Ridzuan SA, Darussalam SE, Hisham NHM, Namasivayam P, Nichole YMY, et al. A review of burden of caregivers of patients with Alzheimer's disease. Malang Neurology Journal; 2019.5(1):42-45. DOI:10.21776/ub.mnj.2019.005.01.7

Oishi M, Mochizuki Y, Shikata E. Corpus callosum atrophy and cerebral blood flow in chronic alcoholics. J Neurol Sci; 1999.162(1):51-55.

Guz W, Pazdan D, Stachyra S, Swieton F, Poreba P, et al. Analysis of corpus callosum size depending on age and sex. Folia Morphologica; 2018:1-26. DOI:10.5603/FM.a2018.0061

Floris DL, Chura LR, Holt RJ, Suckling J, Bullmore ET, Cohen SB, Spencer MD. Psychological Correlates of Handedness and Corpus Callosum Asymmetry in Autism: The left Hemisphere Dysfunction Theory Revisited. J Autism Dev Disord; 2013.43:1758–72. DOI:10.1007/s10803-012-1720-8

Zatz LM, Jernigan TL, Ahumada AJ. Changes on computed cranial tomography with aging: intracranial fluid volume. AJNR Am J Neuroradiol; 1982.3(1):1-11.

Erdoğan AR, Özdikici M, Aydın MD, Aktaş Ö, Dane Ş. Right and left visual cortex areas in healthy subjects with right and left eye dominance. Intern J Neuroscience; 2002.112:517-23.Jinseung K, Si Eun K. Procalcitonin as a diagnostic and prognostic factor for tuberulous meningitis. J Clin Neurol; 2016.1–8. DOI: 10.3988/jcn.2016.12.3.332

Erdoğan AR, Dane Ş, Aydın MD, Özdikici M, Diyarbakırlı S. Sex and handedness differences in size of cerebral ventricles of normal subjects. Intern J Neuroscience; 2004.114:67-73.

Chua SE, Sharma T, Takei N, Murray RM, Woodruff PW. A magnetic resonance imaging study of corpus callosum size in familial schizophrenic subjects, their relatives, and normal controls. Schizophr Res; 2000.41(3):397-403.

Meisenzahl EM, Frodl T, Greiner J, Leinsinger G, Maag KP, et al. Corpus callosum size in schizophrenia-a magnetic resonance imaging analysis. Eur Arch Psychiatry Clin Neurosci; 1999.249(6):305-12.

Clatterbuck RE, Sipos EP. The efficient calculation of neurosurgically relevant volumes from computed tomographic scans using Cavalieri’s direct estimator. Neurosurgery; 1997.40(2):339-42.

Stocchetti N, Croci M, Spagnoli D, Gilardoni F, Resta F, Colombo A. Mass volume measurement in severe head injury: accuracy and feasibility of two pragmatic methods. J Neurol Neurosurg Psychiatry; 2000.68(1):14-17. Towards Matrix. MNJ; 2017.55–60. DOI: 10.21776/ub.mnj.2017.003.02.2

Özdikici M. The estimation of lumbar intervertebral disc volumes before and after exercise using the Cavalieri method. MOJ Anat & Physiol; 2018.5(2):106–08. DOI:10.15406mojap.2018.05.00172

Özdikici M. Volumetric evaluation of the paranasal sinuses with the cavalieri method. Anatomy Physiol Biochem Int J; 2018.5(2):1-3. DOI:10.19080/APBIJ.2018.05.555657

Driesem NR, Raz N. The influence of sex, age, and handedness on corpus callosum morphology: a meta-analysis. Psychobiology; 1995.23(3):240-47.

Jancke L, Staiger JF, Schlaug G, Huang YX, Steinmetz H. The relationship between corpus callosum size and forebrain volume. Cereb Cortex; 1997.7(1):48-56.

Johnson SC, Farnworth T, Pinkston JB, Bigler ED, Blatter DD: Corpus callosum surface area across the human adult life span : effect of age and gender. Brain Res Bull; 1994.35(4):373-77.

Salat D, Ward A, Kaye JA, Janowsky JS. Sex differences in the corpus callosum with aging. Neurobiol Aging; 1997.18(2):191-97.

Allen LS, Richey MF, Chai YM, Gorski RA. Sex differences in the corpus callosum ofthe living human being. J Neurosci; 1991.11(4):933–42.

Byne W, Bleier R, Houston L. Variations in human corpus callosum do not predictgender: a study using magnetic resonance imaging. Behav Neurosci; 1988.102(2):222–27.

Constant D, Ruther H. Sexual dimorphism in the human corpus callosum? A comparison of methodologies. Brain Res; 1996.727(1-2):99-106.

Kertesz A, Polk M, Black SE, Howell J: Sex, handedness, and the morphometry of cerebral asymmetries on magnetic resonance imaging. Brain Res; 1990.530(1):40-48.

Weis S, Weber G, Wenger E, Kimbacher M: The controversy about a sexual dimorphism of the human corpus callosum. Int J Neurosci; 1989.47(1-2):169–73.

Karim SH, Qasim IG, Akkila SS. A Digital Photogrammetric Study of the Corpus Callosum Using MRI in Sulaimani Normal Individuals. Iraqi J Comm Med; 2012.(3):236-38.

Eser O, Haktanır A, Boyacı MG, Doğan FA, Karavelioğlu E. Morphometric Measurement of Corpus Callosum. Türk Nöroşirürji Dergisi; 2011.21(1):14-17.

Kocabıyık N, Kılıç C, Baykal B, Tunalı S, Yalçın B, Bulakbaşı N, Ozan H, Akyol M. Morphometric assessment of corpus callosum and cerebral hemispheres with magnetic resonance ımaging. Trakya Üniv Tıp Fak Derg; 2010.27(4):378-84. DOI:10.5174/tutfd.2009.01514.2


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